China (Mainland)
99% Pure Raw Material CAS 302-79-4 Harga Vitamin A Acid / Tretinoin / Retinoic Acid Cream Bulk Powder CAS NO.302-79-4
- FOB Price: USD: 150.00-200.00 /Kilogram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Available Specifications:
Pharmaceutical Grade(1-10)KilogramPharmaceutical Grade(11-100)Kilogram
- Product Details
Keywords
- Retinoic Acid
- Tretinoin
- Vitamin A Acid
Quick Details
- ProName: 99% Pure Raw Material CAS 302-79-4 Har...
- CasNo: 302-79-4
- Molecular Formula: C20H28O2
- Appearance: Orange yellow crystal powder
- Application: Mainly use in pharmaceutical intermedi...
- DeliveryTime: Abiut 10 days
- PackAge: Aluminum foil bag,fluorinated bottles,...
- Port: Shenzhen port
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99%
- Storage: Store in cool & dry place. Keep away f...
- Transportation: 1) Door to Door Service by DHL/FEDEX/E...
- LimitNum: 1 Gram
- Moisture Content: <0.1%
- Impurity: <0.1%
Superiority
1) Provide costomers with "one-stop"packaging service,from research,development,production,export and so on.
2) We have our own R&D and production base,equipped with advanced production equipment and precision testing the Unitef States Pharmacopoeia(USP),the Britis Pharmacopoeia(EP) and other international advanced standards.All products are through the KOSGER,HALAL certification,the ISO quality management system certification and the HACCP certification.
3) More than 12 years of export experience.
4)Competitive price in China market.
Details
|
Product Name |
Retinoic acid |
|
CAS |
302-79-4 |
|
Molecular Formula |
C20H28O2 |
|
Molecular Weight |
300.44 |
|
Density |
1.011 g/cm3 |
|
Melting Point |
179-184°C(lit.) |
|
Boiling Point |
462.8°C at 760 mmHg |
|
Flash Point |
350.6°C |
|
Vapour Pressure |
7.55E-10mmHg at 25°C |
|
Refractive Index |
1.762 |
|
Storage |
2-8°C |
|
Appearance |
White powder |
Retinoic Acid/Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic.
Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia gene.
This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia.
ATRA acts on PML-RAR to lift this block, causing the immature promyelocytes to differentiate to normal mature blood cells thus decreasing promyelocytes.
Function
1. It is a drug commonly used to treat acne vulgaris and keratosis pilaris.
2. It is available as a cream or gel. It is also used to treat acute promyelocytic leukemia.
3. It can stimulate skin growth and keep epidermic normal.
4. It can slow down skin aging process for solarization, remove tiny wrinkles.
5. It can reduce skin roughness, so skin will become ruddy.
Application
1. Retinoic Acid/Tretinoin is widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc..
2. Retinoic Acid/Tretinoin can be made into tretinoin or retinoic acid cream to cureacne or other unhealthy skin.
3. Retinoic Acid/Tretinoin is used for skin keratinocytes-resistant drugs and cell-induced differentation drug.
